Wrinkles on silk bedding or clothes are inevitable whatever with hand-wash or machine-wash. Silk has a resistance to creasing or wrinkling, most will smooth out naturally. If ironing should become necessary, press the damp bed sheet silk on the reverse side with an iron set on low. Silk charmeuse requires a cool iron to bring back sheen. This is a special care to silk sheet, so please refer to specific care instructions on each label. That will be the most accurate specifications.